Patent · US Active

Pyrrolidine derivatives and their use as complement pathway modulators

US9464081B2 · kind B2 · utility

1Cited by

5References

13Claims

0Family size

Assignee

Novartis AG · CH

Inventors

Stefanie Flohr · Basel, CH
Ulrich Hommel · Mülheim, DE
Edwige Liliane Jeanne Lorthiois · Niffer, FR
Jeurgen Klaus Maibaum · Weil am Rhein, DE
Nils Ostermann · Binzen, DE
Jean Quancard · Huningue, FR
Stefan Andreas Randl · Frankfurt am Main, DE
Olivier Rogel · Hésingue, FR
Anna Vulpetti · Milano, IT

Key dates

Filing date	Jun 27, 2013
Grant date	Oct 11, 2016
Priority date	—
Expiry date	Jun 27, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D403/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a compound of formula (I) a method for manufacturing the compounds of the invention, and its therapeutic uses as a factor D inhibitor for the treatment of ophthalmic diseases. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.