Method for the production of domain antibodies
US9464138B2 · kind B2 · utility
3Cited by
1References
8Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 30, 2010 |
| Grant date | Oct 11, 2016 |
| Priority date | — |
| Expiry date | Jul 23, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/626
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method for producing a domain antibody in a yeast, wherein the formation of disulfide bridges in the domain antibody is promoted. The method encompasses the addition of oxidizing agents, preferably oxidizing metal ions, preferably one or more selected from Cu2+, Fe2+, Fe3+ and Zn2+.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.