Mirac proteins
US9464284B2 · kind B2 · utility
2Cited by
2References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 9, 2010 |
| Grant date | Oct 11, 2016 |
| Priority date | — |
| Expiry date | Mar 9, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This disclosure relates to a method of generating conditionally active biologic proteins from wild type proteins, in particular therapeutic proteins, which are reversibly or irreversibly inactivated at the wild type normal physiological conditions. For example, evolved proteins are virtually inactive at body temperature, but are active at lower temperatures.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.