Characterization of CHO-MIF gene and protein, and use thereof
US9465037B2 · kind B2 · utility
1Cited by
2References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 4, 2012 |
| Grant date | Oct 11, 2016 |
| Priority date | — |
| Expiry date | Oct 4, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is concerned with the specific and highly sensitive detection of specific CHO-MIF (macrophage migration inhibitory factor from Chinese Ovarian Hamster cell line) complexes in the production of anti-MIF antibodies. The present invention is further concerned with the provision of specific antibodies which can be used for a CHO-MIF detection method. The present invention is also concerned with a CHO MIF knockout cell line and use thereof. The present invention also provides preparations obtained from recombinant production in CHO cell lines which are essentially free of CHO-MIF.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.