GLP-1 receptor modulators
US9474755B2 · kind B2 · utility
4Cited by
14References
80Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 24, 2015 |
| Grant date | Oct 25, 2016 |
| Priority date | — |
| Expiry date | Jul 24, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/06139
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36), GLP-1(9-36), and oxyntomodulin, or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where “” represents either or both the R and S form of the compound):where A, B, C, R1, R2, R3, R4, R5, n, p and q are as defined herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.