Luminogen compounds and the use of the same for biosensing and cellular imaging
US9475768B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Mar 16, 2012 |
| Grant date | Oct 25, 2016 |
| Priority date | — |
| Expiry date | Mar 16, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/182
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Provided herein are a luminogen compound of formula (I) including a AIE luminophore moiety conjugated with a maleimide moiety and a use of the same for detecting thiol groups in biomolecules. Also provided is a dye molecule, a biosensor or a bioprobe comprising the luminogen compound of formula (I) in use for detecting thiol groups in biomolecules. The detection method of the present subject matter not only has high thio-selectivity and sensitivity, but also is rapid, convenient and handy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.