Recombinant vector for producing and secreting peptide or protein of interest by propionibacteria and applications thereof
US9476056B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 16, 2012 |
| Grant date | Oct 25, 2016 |
| Priority date | — |
| Expiry date | Dec 10, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/582
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a recombinant vector for expressing and secreting, by a Propionibacterium, at least one eukaryotic peptide or protein of interest, comprising at least: under the control of at least one suitable promoter, at least one nucleic acid sequence encoding a propionibacterial signal peptide and, at least one nucleic acid sequence encoding said eukaryotic peptide or protein of interest; wherein said at least one nucleic acid sequence encoding a propionibacterial signal peptide is translationally fused to said at least one nucleic acid sequence encoding said eukaryotic peptide or protein of interest. The invention further relates to the uses of such a vector in the pharmaceutical field or for the large-scale production of peptides or proteins of interest.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.