Patent · US Active

Isothermal nucleic acid amplification reactor with integrated solid state membrane

US9476102B2 · kind B2 · utility

3Cited by

1References

23Claims

0Family size

Assignee

The Trustees of the University of Pennsylvania · US

Inventors

Haim H. Bau · Swarthmore, US
William R. Abrams · Yeadon, US
Eran Geva · Brooklyn, US
Michael G. Mauk · Wilmington, US
Changchun Liu · Sunnyvale, US
Daneil Malamud · New York, US
Xianbo Ceiu · Beijing, CN

Key dates

Filing date	Feb 15, 2012
Grant date	Oct 25, 2016
Priority date	—
Expiry date	Jan 8, 2033

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB01L2400/065
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

Provided are devices adapted to isolate, amplify, and detect nucleic acids that may be present in a biological sample. The devices can, in some embodiments, isolate, amplify, and detect nucleic acid in a single chamber. In other embodiments, the devices are adapted to isolate and amplify nucleic acids in a reaction chamber, after which the nucleic acids may be communicated to a pervious medium—such as a lateral flow strip—where the user may label and detect the nucleic acids.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.