Method and system for integrated radiological and pathological information for diagnosis, therapy selection, and monitoring

US9478022B2 · kind B2 · utility

Assignee

• Siemens Medical Solutions USA, Inc. · US

Inventors

• Ali Kamen · Skillman, US
• Leo Grady · Yardley, US
• Gianluca Paladini · Skillman, US
• Parmeshwar Khurd · San Jose, US
• Oliver Kutter · Birkenfeld, DE
• Dorin Comaniciu · Princeton Junction, US

Key dates

• Filing date: Aug 22, 2012
• Grant date: Oct 25, 2016
• Expiry date: Aug 12, 2033

Classification

• Technology area (CPC G): Physics
• CPC primary: G06T2207/30004
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A method and system for integrating radiological and pathological information for cancer diagnosis, therapy selection, and monitoring is disclosed. A radiological image of a patient, such as a magnetic resonance (MR), computed tomography (CT), positron emission tomography (PET), or ultrasound image, is received. A location corresponding to each of one or more biopsy samples is determined in the at least one radiological image. An integrated display is used to display a histological image corresponding to the each biopsy samples, the radiological image, and the location corresponding to each biopsy samples in the radiological image. Pathological information and radiological information are integrated by combining features extracted from the histological images and the features extracted from the corresponding locations in the radiological image for cancer grading, prognosis prediction, and therapy selection.