Pyrazolopyrans having herbicidal and pharmaceutical properties

US9480259B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Matthias Witschel · Bad Dürkheim, DE
• Frank Stelzer · Mannheim, DE
• Johannes Hutzler · Waldsee, DE
• Tao Qu · Ludwigshafen, DE
• Thomas Mietzner · Annweiler am Trifels, DE
• Klaus Kreuz · Denzlingen, DE
• Klaus Grossmann · Schifferstadt, DE
• Raphael Aponte · Schifferstadt, DE
• Hans Wolfgang Hoeffken · Ludwigshafen, DE
• Frederick Calo · Goldkronach, DE
• Thomas Ehrhardt · Speyer, DE
• Anja Simon · Weinheim, DE
• Liliana Parra Rapado · Kohlhof, DE

Key dates

• Filing date: May 29, 2013
• Grant date: Nov 1, 2016
• Expiry date: May 29, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/052
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a pyrazolopyran of the general formula I wherein the variables are defined according to the description, including a tautomer, salt, cleavable prodrug, or mixtures thereof, in particular to said pyrazolopyran for use as a medicament and/or an inhibitor of the enzyme serinehydroxymethyltransferase (SHMT). The invention also relates to a process the preparation of a pyrazolopyran of the formula I, to compositions comprising said compound and processes for the preparation of these compositions. Further it relates to use of the pyrazolopyran of formula I as an herbicide as well as to a method of controlling undesired vegetation.