Fermented wheat germ proteins (FWGP) for the treatment of cancer

US9480725B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Joseph Tuscano · Folsom, US
• Derick Lau · Rancho Cordova, US
• Robert O'Donnell · Sacramento, US
• Yunpeng Ma · 安丰镇, CN

Key dates

• Filing date: May 20, 2010
• Grant date: Nov 1, 2016
• Expiry date: Nov 2, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides compositions comprising the component of fermented wheat germ extract (“FWGE”) active in reducing, inhibiting or preventing the proliferation of cancer cells and/or tumors, and methods of making and using such compositions. The active component from FWGE comprises polypeptides having a molecular weight in the range of about 5-100 kiloDaltons (kD), for example, a molecular weight in the range of about 12-50 kD. Exemplary polypeptides from FWGE determined to be active in reducing, inhibiting or preventing the proliferation of cancer cells and/or tumors are listed in Table 1.