Synthetic glucopyranosyl lipid adjuvants
US9480740B2 · kind B2 · utility
24Cited by
165References
10Claims
0Family size
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Key dates
| Filing date | Mar 21, 2014 |
| Grant date | Nov 1, 2016 |
| Priority date | — |
| Expiry date | Jul 1, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/575
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds, particularly, glucopyranosyl lipid adjuvant (GLA) compounds, having the following structure (I) are provided:or a pharmaceutically acceptable salt thereof, wherein L1, L2, L3, L4, L5, L6, L7, L8, L9, L10, Y1, Y2, Y3, Y4, R1, R2, R3, R4, R5, R6, are as defined herein. Pharmaceutical compositions, vaccine compositions, and related methods for inducing or enhancing immune responses, are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.