Nitric oxide delivery devices

US9480785B2 · kind B2 · utility

Assignee

• THE REGENTS OF THE UNIVERSITY OF MICHIGAN · US

Inventors

• Mark E. Meyerhoff · Ann Arbor, US
• Lajos Hofler · Felton, GB
• Dipankar Koley · Ann Arbor, US
• Hang Ren · Beijing, CN

Key dates

• Filing date: Dec 7, 2013
• Grant date: Nov 1, 2016
• Expiry date: Dec 16, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61M2202/0275
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An example of a nitric oxide delivery device includes a medium, a working electrode in contact with the medium, and a reference/counter electrode in contact with the medium and electrically isolated from the working electrode. The medium includes a source of nitrite ions and a Cu(II)-ligand complex. A nitric oxide permeable material separates the medium from an external environment that is to contain blood.