Methods for diagnosing irritable bowel syndrome
US9482672B2 · kind B2 · utility
0Cited by
5References
21Claims
0Family size
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Key dates
| Filing date | Mar 21, 2014 |
| Grant date | Nov 1, 2016 |
| Priority date | — |
| Expiry date | Mar 21, 2034 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/147777
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides an ELISA assay for the determination of serum mast cell β-tryptase levels using rabbit anti-tryptase as the capture antibody and alkaline phosphatase conjugated G3 as the detecting antibody. Luminescent substrate CPSD was used to enhance the assay sensitivity. Also provided are methods for aiding in the diagnosis of irritable bowel syndrome by detecting the serum level of β-tryptase, histamine and/or prostaglandin E2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.