Chemosensory receptor ligand-based therapies
US9486463B2 · kind B2 · utility
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56References
33Claims
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Key dates
| Filing date | Oct 18, 2011 |
| Grant date | Nov 8, 2016 |
| Priority date | — |
| Expiry date | Oct 18, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are methods of modulating hormone concentrations in a subject comprising the administration of a composition comprising a chemosensory receptor ligand, wherein the composition is adapted to deliver the ligand to one or more regions of the intestine of said subject. Also provided are methods directed to the modulation of circulating concentrations of one or more of GLP-1 (total), GLP-1 (active), GLP-2, oxyntomodulin, PYY (total), PYY 3-36, CCK, GIP, insulin, C-peptide, glycentin, uroguanylin amylin, and ghrelin (total), ghrelin (active) and glucagon.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.