Patent · US Active

Compositions comprising polyglutamic acid nanoparticles and CD40 agonists

US9486520B2 · kind B2 · utility

9Cited by

2References

10Claims

0Family size

Assignee

ALLIGATOR BIOSCIENCE AB · SE

Inventors

Carl Arne Krister Borrebaeck · Lund, SE
Sissela Rachel Linn Broos · Malmö, SE
Peter Ellmark · Lund, SE
Malin Marie Lindstedt · Södra Sandby, SE

Key dates

Filing date	Apr 13, 2011
Grant date	Nov 8, 2016
Priority date	—
Expiry date	Aug 11, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2039/55555
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides pharmaceutical compositions comprising an immunostimulatory polypeptide and polyglutamic acid (PGA) nanoparticles, formulated in a pharmaceutically acceptable diluent, carrier or excipient. Such compositions have utility in stimulating the immune system in subjects, with the components capable of interacting synergistically. The invention further provides uses of the compositions of the invention, for example in the treatment of cancer, and kit and components for use in the same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.