Methods for the treatment of leber congenital amaurosis
US9487782B2 · kind B2 · utility
7Cited by
1References
4Claims
0Family size
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Key dates
| Filing date | Nov 18, 2014 |
| Grant date | Nov 8, 2016 |
| Priority date | — |
| Expiry date | Nov 18, 2034 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method for treating a Leber congenital amaurosis in a patient harboring the mutation c.2991+1655 A>G in the CEP290 gene, comprising the step of administering to said patient at least one antisense oligonucleotide complementary to nucleic acid sequence that is necessary for preventing splicing of the cryptic exon inserted into the mutant c.2291+1655 A>G CEP290 mRNA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.