Temperature-sensitive liposomal formulation
US9492385B2 · kind B2 · utility
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30References
7Claims
0Family size
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Key dates
| Filing date | Dec 10, 2008 |
| Grant date | Nov 15, 2016 |
| Priority date | — |
| Expiry date | May 22, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A liposome contains an active agent and has a gel-phase lipid bilayer membrane comprising phospholipid and a surface active agent. The phospholipids are the primary lipid source for the lipid bilayer membrane and the surface active agent is contained in the bilayer membrane in an amount sufficient to increase the percentage of active agent released at the phase transition temperature of the lipid bilayer, compared to that which would occur in the absence of the surface active agent. The surface active agent is present in the lipid bilayer membrane so as to not destabilize the membrane in the gel phase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.