Patent · US Active

Process for the preparation of a chiral compound

US9493428B2 · kind B2 · utility

1Cited by

11References

49Claims

0Family size

Assignee

Sandoz AG · CH

Inventors

Thorsten Wilhelm · Kundl, AT
Martin Langner · Kundl, AT

Key dates

Filing date	Jun 14, 2012
Grant date	Nov 15, 2016
Priority date	—
Expiry date	Jan 3, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D249/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a process for the preparation of a compound of formula (V), in particular posaconazole, wherein said process comprises the steps of (1) providing a mixture comprising a compound of formula (IV), a protic solvent system, and a suitable base; and (2) heating the mixture of (1) to obtain a mixture comprising the compound of formula (V).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.