Spirocyclic dihydro-thiazine and dihydro-oxazine BACE inhibitors, and compositions and uses thereof
US9493485B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Mar 20, 2013 |
| Grant date | Nov 15, 2016 |
| Priority date | — |
| Expiry date | Mar 20, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds are provided having a structure according to Formula (I): wherein A1, A2, A3, Y, R1, R2, R3, R4, R5, R6, m, n and p are defined herein. Further provided are pharmaceutical compositions including the compounds provided and methods of making and using the compounds and compositions as provided, e.g., in the treatment and prevention of various disorders, such as Alzheimer's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.