Fluorinated pyrimidine analogs and methods of use thereof
US9493500B2 · kind B2 · utility
0Cited by
7References
22Claims
0Family size
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Key dates
| Filing date | Mar 15, 2013 |
| Grant date | Nov 15, 2016 |
| Priority date | — |
| Expiry date | Dec 12, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides fluorinated 5-aza-2′-deoxycytidine compounds, such as 2′,2′-difluoro-5-aza-2′-deoxycytidine, compositions that include the compounds, methods for making the compounds, and methods for inhibiting DNA methyltransferase, treating solid tumors, and treating hematologic cancers by administering the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.