Anti-Siglec-15 antibodies
US9493562B2 · kind B2 · utility
1Cited by
54References
14Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 17, 2013 |
| Grant date | Nov 15, 2016 |
| Priority date | — |
| Expiry date | Aug 9, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antibodies and antigen binding fragments that specifically binds to Siglec-15 are described herein. These antibodies or antigen binding fragments may have the ability of inhibiting differentiation of osteoclasts and/or the ability of inhibiting the bone resorption activity of osteoclasts. Compositions and cells expressing anti-Siglec-15 antibodies or antigen binding fragments are also disclosed herewith. Anti-Siglec-15 antibodies may also be useful for the treatment of bone loss, or bone diseases. Methods for the detection or diagnosis of bone loss or bone-related diseases are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.