Hydrolysis of mannose-1-phospho-6-mannose linkage to phospho-6-mannose

US9493756B2 · kind B2 · utility

Assignees

• VIB VZW · BE
• UNIVERSITEIT GENT · BE
• Oxyrane UK Limited · GB
• VRIJE UNIVERSITEIT BRUSSEL · BE

Inventors

• Nico Luc Marc Callewaert · Aalter, BE
• Wouter Vervecken · Landskouter, BE
• Petra Sophie Tiels · Merelbeke, BE
• Han Remaut · Boutersem, BE
• Kathleen Camilla Telesphore Alida Maria Piens · Evergem, BE

Key dates

• Filing date: Sep 29, 2010
• Grant date: Nov 15, 2016
• Expiry date: Apr 28, 2032

Classification

• Technology area (CPC —): General

Abstract

Described herein are methods and genetically engineered cells useful for uncapping a mannose-6-phosphate residue on an oligosaccharide.