Procoagulant molecular decoy for treating hemophilia A or B with or without inhibitor
US9493761B2 · kind B2 · utility
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Key dates
| Filing date | Feb 29, 2012 |
| Grant date | Nov 15, 2016 |
| Priority date | — |
| Expiry date | Feb 29, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/21006
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a pharmaceutical composition including a modified factor Xa (GDXa), said modified GDXa being nonthrombogenic, able to bind to TFPI but not able to bind to phospholipids, for preventing or treating a hemorrhagic accident in a patient with hemophilia A or B with or without inhibitor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.