Use of glycohydrolase 61 protein variants with improved thermostability for processing cellulose
US9493802B2 · kind B2 · utility
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24Claims
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Key dates
| Filing date | Aug 22, 2011 |
| Grant date | Nov 15, 2016 |
| Priority date | — |
| Expiry date | Aug 22, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/52
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides recombinant GH61 proteins obtained from Myceliophtora thermophila, and nucleic acids that encode such proteins. The invention also provides protein fractions isolated from M. thermophila supernatant that have GH61 protein activity. These preparations can be used to increase yield of products from reactions in which a cellulose-containing substrate undergoes saccharification by one or more cellulase enzymes, such as endoglucanase, β-glucosidase, or cellobiohydrolase. Combinations of GH61 protein and cellulases can be used to break down cellulosic biomass into fermentable sugars in the production of ethanol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.