Enzymatic biosensors with enhanced activity retention for detection of organic compounds

US9493805B2 · kind B2 · utility

Assignee

• COLORADO STATE UNIVERSITY RESEARCH FOUNDATION · US

Inventors

• Kenneth F. Reardon · Fort Collins, US
• David S. Dandy · Fort Collins, US
• Michael Fritzsche · Burgdorf, DE
• Thomas K. Wood · Lompoc, US

Key dates

• Filing date: Apr 9, 2008
• Grant date: Nov 15, 2016
• Expiry date: Dec 2, 2029

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/988
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Enzymatic biosensors and methods of producing distal tips for biosensor transducers for use in detecting one or more analytes selected from organic compounds susceptible to dehalogenation, organic compounds susceptible to oxygenation and organophosphate compounds susceptible to hydrolysis are disclosed herein, as well as biosensor arrays, methods of detecting and quantifying analytes within a mixture, and devices and methods for delivering reagents to enzymes disposed within the distal tip of a biosensor.