Method of neonatal serological diagnosis
US9493811B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Aug 10, 2012 |
| Grant date | Nov 15, 2016 |
| Priority date | — |
| Expiry date | Aug 18, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a method for determining the amino acid polymorphisms of heavy gamma chain of immunoglobulins G by a proteomic approach. This method distinguishes the immunoglobulins of the mother and those of the newborn in a blood sample obtained during the first months of the child's life. The invention also relates to the use of this method in the early diagnosis of vertically transmitted diseases in the neonate. The invention also provides peptides distinctive of G3m and IGHG3 alleles, and a kit comprising said peptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.