Chip set-up and high-accuracy nucleic acid sequencing
US9494554B2 · kind B2 · utility
22Cited by
114References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 14, 2013 |
| Grant date | Nov 15, 2016 |
| Priority date | — |
| Expiry date | Feb 21, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/48721
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present disclosure provides devices, systems and methods for sequencing nucleic acid molecules. Nucleic acid molecules can be sequenced with a high accuracy (e.g., greater than 97% in a single pass) using a chip comprising an array of independently addressable nanopore sensors at a density of at least about 500 sites per 1 mm2. An individual nanopore sensor can include a nanopore in a membrane that is adjacent or in proximity to a sensing electrode.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.