Multi-foci laser scanning microscope and use of same for analyzing samples

US9494777B2 · kind B2 · utility

Assignee

• THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO · US

Inventors

• Oleg Rumyantsev · Stanford, US
• Mark J. Schnitzer · Summit, US
• Jerome Anthony-Jean Lecoq · East Palo Alto, US
• Tong Zhang · Palo Alto, US
• Hyun Eui KIM · Cheongju-si, KR
• Joan Savall · Palo Alto, US

Key dates

• Filing date: Aug 22, 2014
• Grant date: Nov 15, 2016
• Expiry date: Jan 16, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G02B21/16
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A multi-foci laser scanning microscope generates a set of time-multiplexed beams that are simultaneously scanned over multiple scan areas of the sample to be observed. A photodetector array associated with the beams detect fluorescence signals from the sample. A processor processes output signals from the photodetector array based on the time-multiplexing of the beams to provide a much wider field of view and reduced crosstalk between neighboring scan areas for more accurate imaging.