Mouse for predicting a behavior of drugs in humans
US9497944B2 · kind B2 · utility
2Cited by
12References
18Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 30, 2013 |
| Grant date | Nov 22, 2016 |
| Priority date | — |
| Expiry date | May 9, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes, such as serum albumin, or portions of genes have been replaced by homologs from another animal, such as a human, to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.