Antimetabolite agent combinations in the treatment of cancer
US9498489B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Apr 19, 2010 |
| Grant date | Nov 22, 2016 |
| Priority date | — |
| Expiry date | Sep 3, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method treating cancer in a subject comprises administering to the subject a therapeutically effective amount of an antimetabolite agent that induces formation of AP sites in cancer cells of the subjects and an amount AP endonuclease inhibitor effective to potentiate the cytotoxicity of the antimetabolite agent to the cancer cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.