Ortho-fluoro substituted compounds for the treatment of metabolic diseases
US9499467B2 · kind B2 · utility
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3References
16Claims
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Key dates
| Filing date | Apr 3, 2012 |
| Grant date | Nov 22, 2016 |
| Priority date | — |
| Expiry date | Apr 3, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C317/44
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There is provided novel fluoro-substituted compounds capable of modulating the G-protein-coupled receptor GPR40, compositions comprising the compounds, and methods for their use for controlling insulin levels in vivo and for the treatment of conditions such as type II diabetes, hypertension, ketoacidosis, obesity, glucose intolerance, and hypercholesterolemia and related disorders associated with abnormally high or low plasma lipoprotein, triglyceride or glucose levels.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.