Patent · US Active

Neprilysin inhibitors

US9499487B2 · kind B2 · utility

11Cited by
25References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 18, 2012
Grant dateNov 22, 2016
Priority date
Expiry dateJan 26, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC09K15/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

In one aspect, the invention relates to compounds having the formula:where R1, R2, R3, X, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.