Amino-substituted imidazopyridazines

US9499547B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Knut Eis · Berlin, DE
• Florian Puehler · Wellesley, US
• Ludwig Zorn · Berlin, DE
• Arne Scholz · Berlin, DE
• Philip Lienau · Berlin, DE
• Mark Jean Gnoth · Mettmann, DE
• Ulf Bömer · Glienicke, DE
• Judith Günther · Berlin, DE
• Marion Hitchcock · Berlin, DE

Key dates

• Filing date: Sep 5, 2012
• Grant date: Nov 22, 2016
• Expiry date: Sep 5, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to amino-substituted imidazopyridazine compounds of general formula (I): in which A, R1, R3 and n are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.