Flaviviruses expressing the prM, E, and NS1 proteins of other flaviviruses and uses thereof
US9499588B2 · kind B2 · utility
8Cited by
2References
6Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 22, 2011 |
| Grant date | Nov 22, 2016 |
| Priority date | — |
| Expiry date | Jul 22, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides flavivirus vaccines that comprise live-attenuated flaviviruses and methods of making and using these vaccines. The flavivirus vaccines described herein possess higher potency due to in situ production of additional immunogens in a way that mimics viral infection and the vaccines have potential for higher potency, reducing costs for production and delivery.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.