Patent · US Active

Human antibodies that bind CD22 and uses thereof

US9499632B2 · kind B2 · utility

7Cited by
5References
42Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 20, 2013
Grant dateNov 22, 2016
Priority date
Expiry dateOct 22, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/92
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure provides isolated monoclonal antibodies that specifically bind to CD22 with high affinity, particularly human monoclonal antibodies. Nucleic acid molecules encoding the antibodies of this disclosure, expression vectors, host cells and methods for expressing the antibodies of this disclosure are also provided. Antibody-partner molecule conjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of this disclosure are also provided. This disclosure also provides methods for detecting CD22, as well as methods for treating various cancers and inflammatory and autoimmune disorders using an anti-CD22 antibody of this disclosure.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.