Undifferentiated cell detection method and complex carbohydrate detection method
US9500650B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Oct 31, 2012 |
| Grant date | Nov 22, 2016 |
| Priority date | — |
| Expiry date | Oct 31, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2400/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An object of the present invention is to provide a method for evaluating a differentiation status of cells using a culture supernatant of stem cells. Provided is “undifferentiation sugar chain marker” composed of the sugar chain structure “Fucα1-2Galβ1-3GlcNAc” or “Fucα1-2Galβ1-3GalNAc” and capable of sensitively determining the undifferentiated state of stem cells using a culture supernatant of stem cells. Also found is BC2LCN lectin or a modified product thereof capable of sensitively recognizing the “undifferentiation sugar chain marker” as excellent “probe for detecting the undifferentiation sugar chain marker” capable of determining the undifferentiation status of cells using a culture supernatant.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.