Animal models and therapeutic molecules
US9504236B2 · kind B2 · utility
27Cited by
34References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 6, 2015 |
| Grant date | Nov 29, 2016 |
| Priority date | — |
| Expiry date | Nov 6, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2015/8518
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention pertains to a transgenic non-human mammal which contains a chimeric immunoglobulin locus containing human variable region gene segments at an endogenous Ig locus operatively linked to non-human mammalian constant region genes, and methods to produce chimeric antibodies therefrom.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.