Methods of selecting biologic-producing cell lines by next generation sequencing
US9506053B2 · kind B2 · utility
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26Claims
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Key dates
| Filing date | Jul 30, 2014 |
| Grant date | Nov 29, 2016 |
| Priority date | — |
| Expiry date | Jul 30, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/14
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An optimized multi-step cell line screening method based on next generation sequencing (NGS) and mass spec (MS) is disclosed. The method helps reduce variants in the biologic-producing cell line and improve the efficiency of cell line development process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.