Modifications for antisense compounds
US9506059B2 · kind B2 · utility
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91References
12Claims
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Key dates
| Filing date | Sep 26, 2014 |
| Grant date | Nov 29, 2016 |
| Priority date | — |
| Expiry date | Sep 26, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/51
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention pertains to modifications for antisense oligonucleotides, wherein the modifications are used to improve stability and provide protection from nuclease degradation. The modifications could also be incorporated into double-stranded nucleic acids, such as synthetic siRNAs and miRNAs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.