Regulated gene expression systems and constructs thereof
US9506072B2 · kind B2 · utility
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Key dates
| Filing date | Mar 26, 2012 |
| Grant date | Nov 29, 2016 |
| Priority date | — |
| Expiry date | Sep 22, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/635
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Compositions and methods for nitrogen sensitive regulation of expression of a transcribable nucleic acid molecule. One aspect provides a nitrogen-sensitive expression system that includes a transcription factor region comprising an NtcA binding site and a core promoter region comprising a RuBisCo promoter or a variant or a functional fragment thereof. Another aspect provides a method of transforming a host cell with an expression system. Also provided are expression cassettes, transformed host cells, and kits.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.