Fluorescent probe for high-sensitivity pancreatic fluid detection, and method for detecting pancreatic fluid

US9506102B2 · kind B2 · utility

Assignee

• THE UNIVERSITY OF TOKYO · JP

Inventors

• Yasuteru Urano · Tokyo, JP
• Masayo Sakabe · Yokohama, JP
• Tetsuo Nagano · Tokyo, JP
• Takeaki Ishizawa · Tokyo, JP
• Suguru Yamashita · Tokyo, JP
• Norihiro Kokudo · Tokyo, JP
• Mako Kamiya · Tokyo, JP

Key dates

• Filing date: May 29, 2013
• Grant date: Nov 29, 2016
• Expiry date: Aug 3, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C09K2211/1088
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A fluorescent probe for detecting pancreatic fluid containing a compound or salt thereof represented by formula (I) below.(In the formula, A represents an amino acid residue or N-substituted amino acid residue, with A forming an amide bond with the adjacent NH in the formula; R1 represents a hydrogen atom or 1 to 4 same or different substituent groups that bond with a benzene ring; R2, R3, R4, R5, R6, and R7 each independently represent a hydrogen atom, a hydroxyl group, an alkyl group, or a halogen atom; R8 and R9 each independently represent a hydrogen atom or an alkyl group; and X represents a C1-C3 alkylene group).