Patent · US Active

Stable MIA/CD-RAP formulation

US9511116B2 · kind B2 · utility

1Cited by

5References

18Claims

0Family size

Assignee

SCIL TECHNOLOGY GMBH · DE

Inventors

Klaus Hellerbrand · Moorenweis, DE
Rainer Sigl · Puchheim, DE

Key dates

Filing date	Oct 26, 2012
Grant date	Dec 6, 2016
Priority date	—
Expiry date	Oct 26, 2032

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to stable aqueous formulations comprising at least 5 mg/mL CD-RAP and a charged amino acid, said amino acid preferably having a net charge at a pH between about 6 and 8. The ingredients of the formulation preferably provide stability over repeated freeze-thaw cycles. In a preferred aspect, the formulation is for use in therapy, preferably for use in the treatment of inflammatory disorders, preferably osteoarthritis. Furthermore, a kit comprising the formulation of the invention is provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.