C17-heteroaryl derivatives of oleanolic acid and methods of use thereof
US9512094B2 · kind B2 · utility
19Cited by
42References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 11, 2014 |
| Grant date | Dec 6, 2016 |
| Priority date | — |
| Expiry date | Dec 11, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J63/008
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are novel C17-heteroaryl derivatives of oleanolic acid, including those of the formula:wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds, for example, as antioxidant inflammation modulators, and compositions thereof are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.