Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
US9512096B2 · kind B2 · utility
3Cited by
102References
53Claims
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Key dates
| Filing date | Dec 21, 2012 |
| Grant date | Dec 6, 2016 |
| Priority date | — |
| Expiry date | Dec 21, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/62
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is related to an improved process for the preparation of amino-substituted 4,5,6,7-tetrahydrobenzothiazole compounds of formula I, such as the compound 2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole. The invention further relates to an improved synthesis of (R)-2-amino-4,5,6,7-tetrahydro-6-(n-propylamino)benzothiazole. The invention also relates to the methods and intermediates associated with the synthetic process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.