Substituted aminopyrimidine compounds and methods of use
US9512114B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 15, 2015 |
| Grant date | Dec 6, 2016 |
| Priority date | — |
| Expiry date | Mar 15, 2035 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the preparation and use of new aminopyrimidine derivatives as drug candidates in free form or in pharmaceutically acceptable salt form and formulations thereof for the modulation of a disorder or disease which is mediated by the activity of the PI3K enzymes. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of disorders or diseases, such as disorders of immunity and inflammation in which PI3K enzymes play a role in leukocyte function, and hyperproliferative disorders associated with PI3K activity, including but not restricted to leukemias and solid tumors, in mammals, especially humans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.