Amino acid sequences directed against GPCRS and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
US9512236B2 · kind B2 · utility
Assignee
Inventors
- Hendrik Adams
- Michael John Scott Saunders
- Johannes Joseph Wilhelmus De Haard
- Christophe Blanchetot
- Martine Smit
- Regorius Leurs
- Sven Jähnichen
- Peter Vanlandschoot
- Francis Descamps
- Maria Gonzalez Pajuelo
- Pascal MERCHIERS
- Catelijne Stortelers
- Philippe Van Rompaey
- David Andre Baptiste Maussang-Detaille
- Maarten Van Roy
Key dates
| Filing date | Oct 12, 2012 |
| Grant date | Dec 6, 2016 |
| Priority date | — |
| Expiry date | Oct 12, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to amino acid sequences that are directed against G-protein coupled receptors (GPCRs), as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The invention also relates to nucleic acids encoding such amino acid sequences and; to methods for preparing such amino acid sequences and polypeptides; to host cells expressing or capable of expressing such amino acid sequences or polypeptides; to compositions, and in particular to pharmaceutical compositions, that comprise such amino acid sequences, polypeptides, nucleic acids and/or host cells; and to uses of such amino acid sequences or polypeptides, nucleic acids, host cells and/or compositions, in particular for prophylactic, therapeutic or diagnostic purposes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.