Method of DNA sequencing by hybridisation
US9512476B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | May 26, 2011 |
| Grant date | Dec 6, 2016 |
| Priority date | — |
| Expiry date | Oct 16, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6874
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Described herein is a method for determining a nucleic acid sequence, said method comprising: a) denaturing a double-stranded nucleic acid molecule corresponding to the said nucleic acid sequence by applying a physical force to the said molecule; b) providing a single-stranded nucleic acid molecule; c) renaturing the said double stranded nucleic acid molecule in the presence of the said single-stranded nucleic acid molecule; and d) detecting a blockage of the renaturation of the double-stranded nucleic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.