Biomarker anaylsis using scodaphoresis
US9512477B2 · kind B2 · utility
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36References
21Claims
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Key dates
| Filing date | May 3, 2013 |
| Grant date | Dec 6, 2016 |
| Priority date | — |
| Expiry date | Jan 10, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6816
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention discloses methods and apparatus for characterizing trace nucleic acids that are biomarkers for disease. The methods and apparatus provide increased sensitivity to such trace nucleic acids, and allow analysis of nucleic acids present in a sample at only 0.01% of the wild-type sequences. The methods and apparatus are also designed for straightforward multiplexing, thus allowing pooling of clinical samples.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.