Methods for indexing samples and sequencing multiple polynucleotide templates
US9512478B2 · kind B2 · utility
14Cited by
60References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 17, 2014 |
| Grant date | Dec 6, 2016 |
| Priority date | — |
| Expiry date | Jun 17, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6869
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to methods for indexing samples during the sequencing of polynucleotide templates, resulting in the attachment of tags specific to the source of each nucleic acid sample such that after a sequencing run, both the source and sequence of each polynucleotide can be determined. Thus, the present invention pertains to analysis of complex genomes (e.g., human genomes), as well as multiplexing less complex genomes, such as those of bacteria, viruses, mitochondria, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.